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such studies mean for human health. Three large
epidemiology studies have been published since
December 2000. Between them, the studies
investigated any possible association between the
use of wireless phones and primary brain cancer,
glioma, meningioma, or acoustic neuroma, tumors of
the brain or salivary gland, leukemia, or other
cancers. None of the studies demonstrated the
existence of any harmful health effects from wireless
phone RF exposures. However, none of the studies
can answer questions about long-term exposures,
since the average period of phone use in these
studies was around three years.
5. What research is needed to decide whether RF
exposure from wireless phones poses a health
risk?
A combination of laboratory studies and
epidemiological studies of people actually using
wireless phones would provide some of the data that
are needed. Lifetime animal exposure studies could
be completed in a few years. However, very large
numbers of animals would be needed to provide
reliable proof of a cancer promoting effect if one
exists. Epidemiological studies can provide data that
is directly applicable to human populations, but 10
or more years follow-up may be needed to provide
answers about some health effects, such as cancer.
This is because the interval between the time of
exposure to a cancer-causing agent and the time
tumors develop — if they do — may be many, many
years. The interpretation of epidemiological studies is
hampered by difficulties in measuring actual RF
exposure during day-to-day use of wireless phones.
Many factors affect this measurement, such as the
angle at which the phone is held, or which model of
phone is used.
6. What is the FDA doing to find out more about
the possible health effects of wireless phone RF?
The FDA is working with the U.S. National Toxicology
Program and with groups of investigators around the
world to ensure that high priority animal studies are
conducted to address important questions about the
effects of exposure to radio frequency energy (RF).
The FDA has been a leading participant in the World
Health Organization International Electromagnetic
Fields (EMF) Project since its inception in 1996. An
influential result of this work has been the
development of a detailed agenda of research needs
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