Agrify PRECISION HDU Manuale operativo - Pagina 9

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Section 5 – Cleaning the HDU

The system can be internally cleaned without any disassembly by following the standard operation procedure for this unit. Clean solvent being

transferred through the system will clean the surfaces and deposit any contaminants into the bottom bowl. In the event of each component

needing to be cleaned individually, adhere to the following protocols. Before disassembling any components on the HDU, ensure the system is

completely vented of pressure/solvent. Additionally, ensure all TCUs are powered oﬀ before opening tanks to atmosphere in accordance with

internal procedures.

Note: When operating in a CGMP environment the operator must perform a cleaning validation in accordance with their internal

procedures.

5.1.

Cleaning

5.1.1.

Verify all solvent has been drained and open the vent valve to ensure the system is at atmospheric pressure.

5.1.2.

Detach all hose connections.

5.1.3.

Remove the clamps and spools one at a time.

5.1.4.

Discard and replace the distillation medium from the ﬁlter column.

5.1.4.

Remove the bottom bowl and, using a stainless-steel food grade cleaning agent, wipe and clean all surfaces of the bowl.

5.1.4.

Using a stainless-steel food grade cleaning agent, wipe and clean all surfaces of the HDU spools.

5.1.4.1.

Verify each tube of the heat exchanger is clean and clean as necessary.

Note: Additional cleaning solutions may be used after proper evaluation.

5.1.5.

Using a food grade cleaning agent safe for use with the gasket material, wipe and clean the gaskets.

5.1.6.

Allow all components to completely dry.

Note: This process can be accelerated by reassembling and pulling vacuum.

5.1.7.

Install the clamps, spools, and bowl.

5.1.8.

Reattach all hose connections.

Model HDU Operational Manual – For Hazardous Environments

Precision® Extraction Solutions

Model HDU Operational Manual – For Hazardous Environments