Alcolizer Druglizer LE5 Руководство пользователя - Страница 4

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2 TEST PRINCIPLE

The Druglizer LE5 Drug Testing System is based on a competitive lateral flow immunoassay

technique where drug molecules that may be present in the oral fluid sample compete with

the same drug attached to the nitrocellulose wicking membrane, for limited binding sites on

tagged drug specific antibodies.

The antibodies are tagged with gold colloids to produce a conjugate with a red colour.

During testing, an oral fluid sample is absorbed onto the oral fluid collector pad. Chemicals

react with the saliva to remove sample interferences and a portion of this sample wicks

onto the conjugate pad where drugs in the sample react with tagged antibody specific for

that drug. The sample continues to wick by capillary forces along the nitrocellulose

membrane, onto which is attached the same drug of interest. If no drug is present in the

oral fluid sample the tagged antibody can bind to the drug bound to the nitrocellulose and a

red line is produced.

If drugs are present in the oral fluid sample at concentrations greater than the cut-off

concentration, the tagged antibody sites will be saturated with the drug and will not be able

to bind to the nitrocellulose bound drug, hence no result is produced. As the drug

concentration in the sample increases the colour intensity of the test line decreases. The

test strip is not intended to be viewed visually rather it is intended to be interrogated by a

meter. The instrument uses a sophisticated algorithm the determine the result.

The Druglizer LE5 is supplied with the following:

•

Druglizer LE5 main module.

•

Druglizer LE5 drug test module.

•

USB cable.

•

Battery Chargers (240VAC and 12VDC vehicle).

•

Silicon protective cover, cartridge plug and wrist strap.

•

Soft shoulder bag or hard plastic carry case (optional).

•

Bluetooth printer (optional).

Updated user Manual and AlcoCONNECT Toolbox can be downloaded from

https://www.alcolizer.com/software-updates/

AlcoCONNECT Toolbox Version 1.6 or above is used to download test logs and configure the

Druglizer LE5. (For AlcoCONNECT Toolbox instructions please refer to AlcoCONNECT Toolbox

User Manual).

Cartridges are not included with the purchase of an instrument. Cartridges are sold

separately in cartons of 25 tests.

REF: Druglizer LE5 Drug Tester User Manual V7.docx

Uncontrolled when printed

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