Gako PM140 Benutzerhandbuch - Seite 5

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1.2. Application and Use

Mixing

The gako PM140 is a user-friendly and practical de-

vice that allows the preparation of formulas in less

than a minute, in a closed mixing jar, with no need

for mixing blades (Figure 3). The studies conducted

by our laboratories show the content uniformity in

all portions of the formulations produced. The stand-

ardized mixing allows for greater stability of emul-

sions, therefore eliminating formulation issues such

as creaming, sedimentation, flocculation, and coa-

lescence. An adequate homogenization also ensures

correct rheological properties, such as the formula-

tion's viscosity and flow.

Deaeration

The gako PM140 deaerates emulsions and gels in

just 45 seconds, ensuring the removal of macrobub-

bles from those formulations (Figure 4).

Melting

The gako PM140 can melt gelatin, suppository, and

vaginal inserts bases in one simple step: the base

can be placed together with the APIs and other nec-

essary ingredients in the PM jar (Figure 5).

Gelatin

bases

Figure 3. Mixing process using the gako PM140.

Figure 4. Deaeration process

using the gako PM140.

Creams

Gums

Mixing

Melting

Deaeration

Suppositories

Before

After

Ointments

Gels

Vaginal Inserts

Before

After

Figure 5. Melting process using

the gako PM140.