Gako PM140 Manuel de l'utilisateur - Page 5

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1.2. Application and Use
Mixing
The gako PM140 is a user-friendly and practical de-
vice that allows the preparation of formulas in less
than a minute, in a closed mixing jar, with no need
for mixing blades (Figure 3). The studies conducted
by our laboratories show the content uniformity in
all portions of the formulations produced. The stand-
ardized mixing allows for greater stability of emul-
sions, therefore eliminating formulation issues such
as creaming, sedimentation, flocculation, and coa-
lescence. An adequate homogenization also ensures
correct rheological properties, such as the formula-
tion's viscosity and flow.
Deaeration
The gako PM140 deaerates emulsions and gels in
just 45 seconds, ensuring the removal of macrobub-
bles from those formulations (Figure 4).
Melting
The gako PM140 can melt gelatin, suppository, and
vaginal inserts bases in one simple step: the base
can be placed together with the APIs and other nec-
essary ingredients in the PM jar (Figure 5).
Gelatin
bases
Figure 3. Mixing process using the gako PM140.
Figure 4. Deaeration process
using the gako PM140.
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Creams
Gums
Mixing
Melting
Deaeration
Suppositories
Before
After
Ointments
Gels
Vaginal Inserts
Before
After
Figure 5. Melting process using
the gako PM140.